My opinion: This book rules.
I'm no Excel "Power User" or anything, but I've used it every day of my life for the past 6 or 7 years, both at work and at home. Even with that, I had no idea Excel could do some of the things that Walkenbach writes about in this book. Before I bought it, I only thought I was staggered by what someone could accomplish with a decent knowledge of Microsoft's ubiquitous spreadsheeting program.
If you're looking for a fantastic overall roundup on Excel, and one that despite its size makes it quite easy to find answers in a pinch, then Excel 2003 Bible is your book. I cannot recommend it highly enough.